Giuseppe Pintucci, PhD - Publications
Publications
| 1. | Ferrari, Giovanni; Cook, Brandoch D; Terushkin, Vitaly; Pintucci, Giuseppe; Mignatti, Paolo. "Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis". Journal of cellular physiology. 2009; 219: 449 (#J0163792) |
| 2. | Gulkarov I; Bohmann K; Cinnante KM; Pirelli L; Yu PJ; Grau JB; Pintucci G; Galloway AC; Mignatti P. "Topical Mitogen-Activated Protein Kinases Inhibition Reduces Intimal Hyperplasia in Arterialized Vein Grafts". Journal of surgical research. 2009; 154: 150 (#J0163044) |
| 3. | Yu, Pey-Jen; Skolnick, Adam; Ferrari, Giovanni; Heretis, Katherine; Mignatti, Paolo; Pintucci, Giuseppe; Rosenzweig, Barry; Diaz-Cartelle, Juan; Kronzon, Itzhak; Perk, Gila; Pass, Harvey I; Galloway, Aubrey C; Grossi, Eugene A; Grau, Juan B. "Correlation between plasma osteopontin levels and aortic valve calcification: potential insights into the pathogenesis of aortic valve calcification and stenosis". Journal of thoracic & cardiovascular surgery. 2009; 138: 196 (#J0173752) |
| 4. | Cook, Brandoch D; Ferrari, Giovanni; Pintucci, Giuseppe; Mignatti, Paolo. "TGF-beta1 induces rearrangement of FLK-1-VE-cadherin-beta-catenin complex at the adherens junction through VEGF-mediated signaling". Journal of cellular biochemistry. 2008; 105: 1367 (#J0157890) |
| 5. | D'Alessio, Silvia; Ferrari, Giovanni; Cinnante, Karma; Scheerer, William; Galloway, Aubrey C; Roses, Daniel F; Rozanov, Dmitri V; Remacle, Albert G; Oh, Eok-Soo; Shiryaev, Sergey A; Strongin, Alex Y; Pintucci, Giuseppe; Mignatti, Paolo. "Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism". Journal of biological chemistry. 2008; 283: 87 (#J0138769) |
| 6. | Yu, P-J; Ferrari, G; Pirelli, L; Galloway, A C; Mignatti, P; Pintucci, G. "Thrombin cleaves the high molecular weight forms of basic fibroblast growth factor (FGF-2): a novel mechanism for the control of FGF-2 and thrombin activity". Oncogene. 2008; 27: 2594 (#J0138338) |
| 7. | Yu PJ; Ferrari G; Pirelli L; Gulkarov I; Galloway AC; Mignatti P; Pintucci G. "Vascular injury and modulation of MAPKs: A targeted approach to therapy of restenosis". Cellular signalling. 2007; 19: 1359 (#J0126251) |
| 8. | Yu, Pey-Jen; Ferrari, Giovanni; Galloway, Aubrey C; Mignatti, Paolo; Pintucci, Giuseppe. "Basic fibroblast growth factor (FGF-2): the high molecular weight forms come of age". Journal of cellular biochemistry. 2007; 100: 1100 (#J0126252) |
| 9. | Ferrari, Giovanni; Pintucci, Giuseppe; Seghezzi, Graziano; Hyman, Kevin; Galloway, Aubrey C; Mignatti, Paolo. "VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis". Proceedings of the National Academy of Sciences of the United States of America. 2006; 103: 17260 (#J0122584) |
| 10. | Gulkarov, Iosif; Pintucci, Giuseppe; Bohmann, Katja; Saunders, Paul C; Sullivan, Raymond F; Ferrari, Giovanni; Mignatti, Paolo; Galloway, Aubrey C. "Mechanisms of c-reactive protein up-regulation in arterialized vein grafts". Surgery. 2006; 139: 254 (#J0126253) |
| 11. | Pintucci G; Saunders PC; Gulkarov I; Sharony R; Kadian-Dodov DL; Bohmann K; Baumann FG; Galloway AC; Mignatti P. "Anti-proliferative and anti-inflammatory effects of topical MAPK inhibition in arterialized vein grafts". FASEB journal. 2006; 20: 398 (#J0112602) |
| 12. | Pirelli L; Yu P-J; Gulkarov I; Galloway AC; Mignatti P; Pintucci G. "Inhibition of mitogen-activated protein kinases (MAPKs) as a strategy to prevent intimal hyperplasia following cardiovascular interventions". Vascular Disease Prevention. 2006; 3: 173 (#J0118973) |
| 13. | Sharony, Ram; Pintucci, Giuseppe; Saunders, Paul C; Grossi, Eugene A; Baumann, F Gregory; Galloway, Aubrey C; Mignatti, Paolo. "Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2". American journal of physiology. Heart & circulatory physiology. 2006; 290: H1651 (#J0126254) |
| 14. | Pintucci G; Yu PJ; Saponara F; Kadian-Dodov DL; Galloway AC; Mignatti P. "PDGF-BB induces vascular smooth muscle cell expression of high molecular weight FGF-2, which accumulates in the nucleus". Journal of cellular biochemistry. 2005; 95: 1292 (#J0103892) |
| 15. | Saunders PC; Pintucci G; Bizekis CS; Sharony R; Hyman KM; Saponara F; Baumann FG; Grossi EA; Colvin SB; Mignatti P; Galloway AC. "Vein graft arterialization causes differential activation of mitogen-activated protein kinases". Journal of thoracic & cardiovascular surgery. 2004; 127: 1276 (#J0070254) |
| 16. | Adachi M; Gazel A; Pintucci G; Shuck A; Shifteh S; Ginsburg D; Rao LS; Kaneko T; Freedberg IM; Tamaki K; Blumenberg M. "Specificity in Stress Response: Epidermal Keratinocytes Exhibit Specialized UV-Responsive Signal Transduction Pathways". DNA & cell biology. 2003; 22: 665 (#J0053001) |
| 17. | Bizekis C; Pintucci G; Derivaux CC; Saponara F; Kim JH; Hyman KM; Grossi EA; Baumann FG; Mignatti P; Galloway AC. "Activation of mitogen-activated protein kinases during preparation of vein grafts and modulation by a synthetic inhibitor". Journal of thoracic & cardiovascular surgery. 2003; 126: 659 (#J0053073) |
| 18. | McAllister SS; Becker-Hapak M; Pintucci G; Pagano M; Dowdy SF. "Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions". Molecular & cellular biology. 2003; 23: 216 (#J0114706) |
| 19. | Pintucci G; Yu PJ; Sharony R; Baumann FG; Saponara F; Frasca A; Galloway AC; Moscatelli D; Mignatti P. "Induction of stromelysin-1 (MMP-3) by fibroblast growth factor-2 (FGF-2) in FGF-2-/- microvascular endothelial cells requires prolonged activation of extracellular signal-regulated kinases-1 and -2 (ERK-1/2)". Journal of cellular biochemistry. 2003; 90: 1015 (#J0069618) |
| 20. | Green, D; Rafii, S; Froum, S; Pinnell, J; Mignatti, P; Pintucci, G. "Trophic effects of platelets on cultured endothelial cells are mediated by platelet-associated fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF)". Blood. 2002; 100: 681A (#J0050623) |
| 21. | Hyman KM; Seghezzi G; Pintucci G; Stellari G; Kim JH; Grossi EA; Galloway AC; Mignatti P. "Transforming growth factor-beta1 induces apoptosis in vascular endothelial cells by activation of mitogen-activated protein kinase". Surgery. 2002; 132: 173 (#J0045995) |
| 22. | Pintucci G; Moscatelli D; Saponara F; Biernacki PR; Baumann FG; Bizekis C; Galloway AC; Basilico C; Mignatti P. "Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells". FASEB journal. 2002; 16: 598 (#J0047698) |
| 23. | Pintucci, G; Moscatelli, D; Saponara, F; Biernacki, PR; Baumann, FG; Bizekis, C; Galloway, AC; Basilico, C; Mignatti, P. "Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells". FASEB journal. 2002; 16: U173 (#J0030590) |
| 24. | Pintucci, Giuseppe; Froum, Scott; Pinnell, Jared; Mignatti, Paolo; Rafii, Shahin; Green, David. "Trophic effects of platelets on cultured endothelial cells are mediated by platelet-associated fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF)". Thrombosis & haemostasis. 2002; 88: 834 (#J0163793) |
| 25. | Pintucci, G; Froum, S; Rafii, S; Mignatti, P; Green, D. "Trophic effect of platelets on cultured endothelial cells is mediated by FGF-2 and VEGF [Abstract]". Blood. 2001; 98: 56B (#J0101474) |
| 26. | Das D; Pintucci G; Stern A. "MAPK-dependent expression of p21(WAF) and p27(kip1) in PMA-induced differentiation of HL60 cells". FEBS letters. 2000; 472: 50 (#J0005428) |
| 27. | Klein S; Carroll JA; Chen Y; Henry MF; Henry PA; Ortonowski IE; Pintucci G; Beavis RC; Burgess WH; Rifkin DB. "Biochemical analysis of the arginine methylation of high molecular weight fibroblast growth factor-2". Journal of biological chemistry. 2000; 275: 3150 (#J0004789) |
| 28. | Seghezzi, G; Pintucci, G; Yun, J; Steinberg, BM; Ferdinand, B; Grossi, EA; Baumann, FG; Colvin, SB; Galloway, AC; Mignatti, P. "Transforming growth factor beta 1 (TGF-b1) induces a growth factor cascade that results in extracellular-regulated kinase (ERK) and p38 mitogen-activated protein kinase activation in endothelial cells [abstract]". Journal of the American College of Cardiology. 2000; 35: 296A (#J0046113) |
| 29. | Kaneko, T; Komine, M; Tamaki, K; Gazel, A; Pintucci, G; Freedberg, IM; Blumenberg, M. "In vivo activation of the UV-responsive signal transduction cascade in human epidermal keratinocytes [Abstract]". Journal of investigative dermatology. 1999; 112: 563 (#J0096326) |
| 30. | Pintucci G; Steinberg BM; Seghezzi G; Yun J; Apazidis A; Baumann FG; Grossi EA; Colvin SB; Mignatti P; Galloway AC. "Mechanical endothelial damage results in basic fibroblast growth factor-mediated activation of extracellular signal-regulated kinases". Surgery. 1999; 126: 422 (#J0004587) |
| 31. | Seghezzi G; Patel S; Ren CJ; Gualandris A; Pintucci G; Robbins ES; Shapiro RL; Galloway AC; Rifkin DB; Mignatti P. "Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis". Journal of cell biology. 1998; 141: 1659 (#J0003160) |
| 32. | Bikfalvi A; Klein S; Pintucci G; Rifkin DB. "Biological roles of fibroblast growth factor-2". Endocrine reviews. 1997; 18: 26 (#J0005429) |
| 33. | Seghezzi, G; Patel, S; Ren, CJ; Pintucci, G; Gualandris, A; Robbins, E; Shapiro, RL; Galloway, AC; Rifkin, DB; Mignatti, P. "Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism of angiogenesis [Abstract]". Molecular biology of the cell. 1997; 8: 1335 (#J0093523) |
| 34. | Pintucci G; Bikfalvi A; Klein S; Rifkin DB. "Angiogenesis and the fibrinolytic system". Seminars in thrombosis & hemostasis. 1996; 22: 517 (#J0005431) |
| 35. | Pintucci G; Quarto N; Rifkin DB. "Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution". Molecular biology of the cell. 1996; 7: 1249 (#J0005430) |
| 36. | Seghezzi, G; Patel, S; Pintucci, G; Galloway, A; Rifkin, D; Mignatti, P. "Autocrine regulation of vascular endothelial growth factor (VEGF) expression by fibroblast growth factor-2 (FGF-2) [Abstract]". Molecular biology of the cell. 1996; 7: 2045 (#J0093903) |
| 37. | Bikfalvi A; Klein S; Pintucci G; Quarto N; Mignatti P; Rifkin DB. "Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms". Journal of cell biology. 1995; 129: 233 (#J0001059) |
| 38. | Iacoviello L; Kolpakov V; Salvatore L; Amore C; Pintucci G; de Gaetano G; Donati MB. "Human endothelial cell damage by neutrophil-derived cathepsin G. Role of cytoskeleton rearrangement and matrix-bound plasminogen activator inhibitor-1". Arteriosclerosis, thrombosis, & vascular biology. 1995; 15: 2037 (#J0027830) |
| 39. | Pintucci G; Iacoviello L; Castelli MP; Amore C; Evangelista V; Cerletti C; Donati MB. "Cathepsin G--induced release of PAI-1 in the culture medium of endothelial cells: a new thrombogenic role for polymorphonuclear leukocytes?". Journal of laboratory & clinical medicine. 1993; 122: 69 (#J0027831) |
| 40. | Pintucci G; Iacoviello L; Amore C; Evangelista V; Cerletti C; Donati MB. "Cathepsin G, a polymorphonuclear cell protease, affects the fibrinolytic system by releasing PAI-1 from endothelial cells and platelets". Annals of the New York Academy of Sciences. 1992; 667: 286 (#J0027832) |
| 41. | Cicero R; Gallone A; Maida I; Pintucci G. "Effects of copper on the tyrosinase of liver pigment cells from Rana esculenta L". Comparative biochemistry & physiology. Pt. B. 1990; 96: 393 (#J0027835) |
| 42. | Mussoni L; Pintucci G; Romano G; De Benedetti F; Massa M; Martini A. "Decreased fibrinolytic activity in juvenile chronic arthritis". Annals of rheumatic diseases. 1990; 49: 973 (#J0027833) |
| 43. | Pintucci G; Manzionna MM; Maida I; Boffi M; Boffoli D; Gallone A; Cicero R. "Morpho-functional characterization of cultured pigment cells from Rana esculenta L. liver". In vitro cellular & developmental biology. 1990; 26: 659 (#J0027834) |
| 44. | Bertele V; Mussoni L; Pintucci G; del Rosso G; Romano G; de Gaetano G; Libretti A. "The inhibitory effect of aspirin on fibrinolysis is reversed by iloprost, a prostacyclin analogue". Thrombosis & haemostasis. 1989; 61: 286 (#J0027836) |
| 45. | Cicero R; Mallardi A; Maida I; Gallone A; Pintucci G. "Melanogenesis in the pigment cells of Rana esculenta L. liver: evidence for tyrosinase-like activity in the melanosome protein fraction". Pigment cell research. 1989; 2: 100 (#J0027837) |
| 46. | Bertele V; Mussoni L; del Rosso G; Pintucci G; Carriero MR; Merati MG; Libretti A; de Gaetano G. "Defective fibrinolytic response in atherosclerotic patients--effect of iloprost and its possible mechanism of action". Thrombosis & haemostasis. 1988; 60: 141 (#J0027838) |
| 47. | Cicero R; Maida I; Mallardi A; Pintucci G; Gallone A. "[Demonstration of a tyrosinase type activity in Kupffer cells of Rana esculenta L.]". Bollettino della Societa Italiana di Biologia Sperimentale. 1988; 64: 203 (#J0027839) |
| 48. | Dejana E; Breviario F; Erroi A; Bussolino F; Mussoni L; Gramse M; Pintucci G; Casali B; Dinarello CA; Van Damme J; et al.. "Modulation of endothelial cell functions by different molecular species of interleukin 1". Blood. 1987; 69: 695 (#J0027840) |
| 49. | Grames M; Breviario F; Pintucci G; Millet I; Dejana E; van Damme J; Donati MB; Mussoni L. "Enhancement by interleukin-1 (IL-1) of plasminogen activator inhibitor (PA-I) activity in cultured human endothelial cells". Biochemical & biophysical research communications. 1986; 139: 720 (#J0027841) |
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